Secondary Effects

Development of Cushingoid state

Within a few months after prednisone treatment began Pearl took on this typical appearance, gaining about 30 pounds. She recovered some of her normal appearance in 2002 but a return to higher doses of prednisone brought back the Cushingoid appearance. The bloat was severe enough to cause protrusion of internal body parts through her vaginal opening on a few occasions – this was a temporary condition that corrected itself within a week or so without special treatment or surgery.

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