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Impressum
INDEX
Intro
A Medical Emergency
Background
Unexplained weight loss
Unusual stress
Jaw claudication
More unusual stress
Pain all over
Elevated alkaline phosphatase
Temporary loss of vision in right eye
Synopsis of Pearl’s medical history before 12/11/98
Treatment
Disease Flares
Legs claudication
Right heel ulcer
Left arm claudication
Left heel ulcer
Rotator cuff tendonitis and bursitis, both shoulders and momentary loss of all vision
Expanding management tools
Events log
Spreadsheet
C-reactive protein
Internet support group
Medical journal articles
Dr. Sohan S. Hayreh’s paper
Diagnostic tests
Diagnosing GCA
X-ray
Doppler scan
Biopsy
CT or CAT scan
Diagnosing unusual conditions
Thyroid
Doppler scan
Arteriogram
Hyperbaric oxygen (HBO)
EKG, Echocardiogram, Stress tests
Berkeley Heart Panel test
MRI
Lipids
Interluken-6 (IL-6) test
Chromosome Analysis and FISH test
Adrenal, Pituitary Glands test
Allergen test
MRA
PET Scan
Upper endoscopy and biopsy
Bone density scan
Conductivity test
Homocysteines test
Fluorescein angiography (FA)
Ultrasound of aorta
IgG
Chromosome, JAK 2, Bone marrow
B12, Folate, Cryoglobulins, Cryofibrinogen, Monoclonal Protein
64 slice CT heart and aorta scan
CT Scan and X-rays of chest and abdomen
Secondary effects
Fluid retention
Hypertension
Muscle weakness
Loss of muscle mass
Osteoporosis
Vertebral compression fracture
Aseptic necrosis of femoral and humeral heads
Peptic ulcer with possible perforation and hemorrhage
Pancreatitis
Abdominal distention
Impaired wound healing
Thin fragile skin
Petechiae and ecchymoses
Vertigo
Headache
Development of Cushingoid state
Secondary adrenocortical and pituitary unresponsiveness
Manifestations of latent diabetes mellitus
Posterior subcapsular cataracts
Exophthalmos
Urticaria and other allergic, anaphylactic or hypersensitivity reactions
Smoldering inflammation
Medications and options for reducing prednisone (steroid-sparing)
Methotrexate with prednisone
Alternate day prednisone therapy with or without methotrexate
Aspirin
Etanercept, azathioprine, cyclophosphamide, dapsone, adalimumab and rituximab
Imatinib mesylate
Unanticipated death
Cause of Pearl’s death
Florida death certificate
Hospital ER physician’s report
James’ conclusions
Speculation about cause of GCA
Appendix 1
Bibliography of medical journal articles of steroid-sparing medications for GCA
Appendix 2
Bibliography of medical journal articles posing theories for cause of GCA
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